Thermo Fisher Scientific CATSPER3 Polyclonal Antibody
CATSPER3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunohistochemistry에 적합하며, 사람 시료 반응성. 동결건조 형태로 제공되며, 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
- Publications: 3 publications
Immunohistochemistry (IHC)
- Tested Dilution: 1:200–1:2,000
- Publications: 3 publications
Miscellaneous PubMed (Misc)
- Publications: View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human Cation channel sperm associated protein 3 (CATSPER3) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CATSPER3.
Target Information
CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization, and cAMP-mediated calcium influx in sperm.
There are four CatSper proteins in mammalian sperm: CatSper1, CatSper2, CatSper3, and CatSper4.
CatSper proteins contain a six-transmembrane-spanning segment and exhibit the voltage-dependent Ca²⁺ channel four-repeat structure. They assemble into a heterotetrameric complex forming an alkalinization-activated Ca²⁺-selective channel.
Mutations in CatSper family genes can result in male infertility. CatSper3 plays a key role in hyperactivated motility of sperm cells, essential for fertilization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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