Thermo Fisher Scientific TMEM106A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (IHC)

5 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A 14 amino acid synthetic peptide near the amino terminus of human TMEM106A if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM106A,uniProtId:Q96A25-1,ncbiNodeId:9606,antigenRange:1,antigenLength:262,antigenImageFileName:PA5-34352_TMEM106A_Q96A25-1_Rabbit.svg,antigenImageFileNamePDP:PA5-34352_TMEM106A_Q96A25-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2551704

Product Specific Information

A suggested positive control is A-20 cell lysate.

PA5-34352 can be used with blocking peptide PEP-1395.

Target Information

Transmembrane protein 106A (TMEM106A) is a single-pass transmembrane protein that is closely related to TMEM106B, a protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual roles of TMEM106A and TMEM106B are still undetermined; however, as TMEM106B is involved in FTLD, it is possible that TMEM106A may also be a risk factor for FTLD.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.