Thermo Fisher Scientific PPM1B Monoclonal Antibody (OTI3E8), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.

Target Information

The PPM1B gene encodes a member of the PP2C family of serine/threonine protein phosphatases, which act as negative regulators of cell stress response pathways.
This phosphatase dephosphorylates cyclin-dependent kinases (CDKs), implicating it in cell cycle control. Overexpression can induce cell growth arrest or apoptosis.
Alternative splicing produces multiple transcript variants encoding different isoforms. Some additional variants are described but may not represent full-length sequences.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.