Thermo Fisher Scientific GSK3-beta Polyclonal Antibody
GSK3-beta 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 적합. Human, Mouse 반응성 확인. 항원 친화 크로마토그래피로 정제된 액상 항체이며, 4°C에서 보관. 에너지 대사 및 신호전달 연구에 활용 가능.
- 카탈로그번호
- A302049A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human glycogen synthase kinase-3 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat and X. laevis
Target Information
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development, and body pattern formation. It negatively regulates glucose homeostasis and participates in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways.
GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, inhibiting Wnt signaling by mediating beta-catenin degradation. It is also involved in Hedgehog, Notch, and insulin signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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