Thermo Fisher Scientific CX3CL1 Polyclonal Antibody
CX3CL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·생쥐·랫트에 반응합니다. WB, IHC, ICC, Flow, ELISA 등 다양한 응용 가능. Protein A로 정제된 고순도 액상 제품이며 -20°C에서 보관.
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Thermo Fisher Scientific CX3CL1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:10 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CX3CL1, amino acids 301–397 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chemokines are a family of proteins involved in leukocyte trafficking during immune surveillance and inflammation. CX3CL1, a CX3C chemokine, mediates leukocyte adhesion and migration via its membrane-bound and soluble forms. Studies indicate CX3CL1 suppresses production of nitric oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting a neuroprotective role. Its receptor, CX3CR1, also serves as a co-receptor for HIV-1 and HIV-2, and this interaction can be inhibited by CX3CL1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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