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Thermo Fisher Scientific SMN1 Polyclonal Antibody
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SMN1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 사용 가능. 마우스 시료에 반응하며, 합성 펩타이드(aa 120-170)로 면역화. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 보관 권장.
- 판매단위
- pk
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563,100원VAT 포함 619,410원
Thermo Fisher Scientific · Thermo Fisher Scientific SMN1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 120–170 of mouse SMN1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide shares 95% identity with rat sequence.
- Specificity: SMN1.
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This region contains multiple genes and repetitive elements, making it prone to rearrangements and deletions.
Both telomeric and centromeric copies encode the same survival motor neuron protein.
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), essential components of the spliceosome.
Mutations in SMN1 are associated with spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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