Thermo Fisher Scientific Symplekin Polyclonal Antibody
Thermo Fisher Scientific의 Symplekin Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 WB 및 IHC에 사용 가능. 합성 펩타이드 항원을 기반으로 제작된 비결합형 토끼 Ig 항체로, 연구용에 적합. 장기 보관 시 -20°C에서 안정적 유지.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: View 1 publication
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: View 1 publication
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 200–250 of mouse Symplekin conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and human.
- Specificity: Symplekin.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 is detected in thymus, lymph nodes, tonsils, spleen, and certain brain and gut regions.
CD4 functions to initiate or augment early T-cell activation via association with the T-cell receptor complex and Lck kinase. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases.
Multiple alternatively spliced transcripts have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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