Thermo Fisher Scientific EEA1 Polyclonal Antibody
EEA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot 및 Immunoprecipitation에 사용 가능. 인간 및 생쥐 반응성, 항원 친화 크로마토그래피로 정제, 4°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1361 and 1411 of human early endosome antigen 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Early endosomal antigen 1 (EEA1) is a 162 kDa membrane-bound protein specific to the early endosome and essential for fusion between early endocytic vesicles. Early endosomes fuse with endocytic vesicles to redistribute extracellular compounds.
EEA1 contains zinc-finger-like domains in both amino and carboxyl-terminal regions, similar to those found in nucleic acid binding proteins. The carboxyl-terminal zinc-finger-like domain is conserved among several non-nuclear proteins involved in intracellular trafficking.
This authentic zinc-binding domain is critical for intracellular localization of EEA1. Membrane association of EEA1 depends on phosphatidyl 3-kinase activity; inhibitors cause dissociation from early endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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