Thermo Fisher Scientific SERPINC1 Polyclonal Antibody
인간, 생쥐, 랫트 시료에서 SERPINC1 단백질을 검출하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 실험에 적합. Affinity chromatography로 정제된 액상 항체로, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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- PA5102428
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SERPINC1 (Accession P01008), corresponding to amino acid residues S236–Q286 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851833 |
Product Specific Information
Antibody detects endogenous levels of total SERPINC1.
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. It inhibits thrombin and other activated serine proteases in the coagulation system, regulating the blood coagulation cascade. The protein includes two functional domains: the heparin-binding domain at the N-terminus and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified in this gene, many of which are associated with antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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