Thermo Fisher Scientific Phospho-4EBP1 (Ser65) Polyclonal Antibody
인간 4EBP1 Ser65 인산화 부위를 인식하는 Rabbit Polyclonal Antibody입니다. Western blot과 ELISA에 사용 가능하며, 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관하며 연구용으로 적합합니다.
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Thermo Fisher Scientific Phospho-4EBP1 (Ser65) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphorylated peptide around S65 of human Phospho-eIF4EBP1-S65 (NP_0040861) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914830 |
Product Specific Information
- Positive test controls include: 293T
- Immunogen sequence: RNSPV
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation.
Phosphorylation in response to signals such as UV irradiation and insulin leads to dissociation from eIF4E and activation of mRNA translation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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