Thermo Fisher Scientific Phospho-PAR1 (Tyr420) Polyclonal Antibody
Phospho-PAR1 (Tyr420) 폴리클로날 항체로 인간, 생쥐, 랫트 시료에서 인산화된 Thrombin Receptor를 검출. Western blot에 적합하며, 고순도 정제 및 안정적 PBS/glycerol 저장용액 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human F2R (Accession P25116), corresponding to amino acid residues around phosphorylated Tyr420. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816568 |
Product Specific Information
This antibody detects endogenous levels of Thrombin Receptor only when phosphorylated at Tyr420.
Target Information
Thrombin is a serine protease involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors including PAR-1, PAR-2, and PAR-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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