Thermo Fisher Scientific Phospho-PAR1 (Tyr420) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human F2R(Accession P25116), corresponding to amino acid residues around phosphorylated Tyr420. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PAR1,uniProtId:P25116-1,ncbiNodeId:9606,antigenRange:420,antigenLength:425,antigenImageFileName:PA5-105095_PAR1_P25116-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105095_PAR1_P25116-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816568

Product Specific Information

Antibody detects endogenous levels of Thrombin Receptor only when phosphorylated at Tyr420.

Target Information

Thrombin is a serine protease that is involved in platelet aggregation and blood coagulation. It is cleaved from its precursor, prothrombin, and converts fibrinogen to fibrin in the final step of the clotting cascade. Thrombin mediates its regulatory effects by activating cell surface G-protein coupled receptors which include PAR-1, PAR-2 and PAR3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.