Thermo Fisher Scientific Growth Hormone Polyclonal Antibody
Thermo Fisher Scientific의 Growth Hormone Polyclonal Antibody는 인간 성장호르몬에 특이적인 토끼 IgG 항체로, Western blot 및 IHC 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고농도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA527360
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–217 of Human Growth Hormone |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544836 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLaS3, Raji
- Predicted reactivity: Rhesus Monkey (96%), Chimpanzee (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Human growth hormone (hGH) belongs to the somatotropin/prolactin family, essential for growth control.
The GH1 gene and four related genes are located on chromosome 17, sharing high sequence identity.
Alternative splicing produces five isoforms (~19–24 kDa).
HGH is secreted by pituitary somatotroph cells and binds cytokine receptor subfamily membrane receptors.
Its main role is to stimulate liver and other tissues to secrete IGF-1, promoting muscle differentiation, proliferation, amino acid uptake, and protein synthesis.
Mutations or deletions in this gene cause growth hormone deficiency and short stature.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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