Thermo Fisher Scientific Lyn Polyclonal Antibody
Thermo Fisher Scientific의 Lyn Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 항체로, Western blot, IHC, ICC/IF, IP에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA527361
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | 1 publication |
| Immunoprecipitation (IP) | 1:100–1:500 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–303 of Human LYN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544837 |
Product Specific Information
- Recommended positive controls: HeLa, CD44-knockout HeLa, Raji, K562, THP-1
- Predicted reactivity: Mouse (94%), Rat (95%), Xenopus laevis (83%), Sheep (87%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Lyn proto-oncogene (Lcl/Yes related novel protein tyrosine kinase)는 인간 염색체 8번에 위치한 Lyn 유전자에 의해 암호화되며, Src family kinase에 속하는 비수용체성 티로신 키나아제입니다.
주로 조혈세포(lymphoid 및 myeloid 세포)에서 발현되며, T 림프구에서는 제외됩니다.
Lyn은 B 세포 수용체 신호전달, 비만세포 신호전달, 그리고 Epithelial-Mesenchymal Transition (EMT) 조절 등 다양한 생물학적 과정에서 중요한 역할을 합니다.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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