Thermo Fisher Scientific G6PD Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2
• Predicted reactivity: Rat (93%), Xenopus laevis (82%), Rabbit (95%), Sheep (92%), Rhesus Monkey (99%), Bovine (95%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes glucose-6-phosphate dehydrogenase (G6PD), a cytosolic enzyme encoded by a housekeeping X-linked gene. Its main function is to produce NADPH, a key electron donor in defense against oxidizing agents and in reductive biosynthetic reactions.
G6PD shows high genetic diversity, with many variants resulting from missense mutations that affect enzyme activity and clinical symptoms. Deficiency may cause neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been identified.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.