Thermo Fisher Scientific BTK Monoclonal Antibody (OTI10E10), TrueMAB
인간 BTK 단백질을 인식하는 마우스 단클론 항체로 ELISA 및 Luminex 분석에 사용 가능. 고순도의 액상 형태로 제공되며, PBS 버퍼와 트레할로스가 포함되어 안정적. 연구용으로만 사용 가능하며, 면역 신호전달 연구에 적합.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:100 – 1:1,000
Luminex (LUM)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10E10 |
| Immunogen | Full length human recombinant protein of human BTK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Additional Formats:
- Biotin conjugate available
- Custom conjugation available upon request
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
BTK interacts with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9, which are critical in innate and adaptive immunity. It also associates with TLR4 signaling proteins including MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting involvement in lipopolysaccharide signal transduction.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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