Thermo Fisher Scientific BTK Monoclonal Antibody (OTI13E5), TrueMAB
BTK 단백질을 표적으로 하는 마우스 단클론 항체로, ELISA 및 Luminex 분석에 사용 가능. 인간 시료에 반응하며, HEK293T 세포에서 발현된 전장 BTK 단백질로 면역화됨. 액상 형태로 제공되며, -20°C에서 보관. 연구용 전용 제품.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:100 – 1:1,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13E5 |
| Immunogen | Full length human recombinant BTK protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Additional Formats
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily. Mutations in the BTK gene are associated with developmental blocks in human B-cell ontogeny and immunodeficiency disorders. BTK interacts with toll-like receptor (TLR) family members such as TLR4, TLR6, TLR8, and TLR9, which are essential in innate and adaptive immunity. It also interacts with MyD88, TIRAP, and IRAK, but not TRAF-6, indicating its role in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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