Thermo Fisher Scientific BTK Monoclonal Antibody (OTI1H7), TrueMAB
BTK 단백질을 인식하는 Mouse monoclonal antibody. ELISA 및 Luminex 분석에 적합하며, Human 시료 반응성. 고순도 친화 크로마토그래피 정제, PBS buffer(5% trehalose, 0.05% sodium azide 포함) 보존. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| ELISA (ELISA) | 1:100 - 1:1,000 | |
| Luminex (LUM) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H7 |
| Immunogen | Full length human recombinant protein of human BTK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases.
Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
It interacts with members of the toll-like receptor (TLR) family such as TLR4, TLR6, TLR8, and TLR9, which are critical in innate and adaptive immunity.
BTK also interacts with key proteins in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting its role in lipopolysaccharide signal transduction.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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