Thermo Fisher Scientific alpha-1b Adrenergic Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting human alpha-1b adrenergic receptor. Suitable for IHC(P) and ELISA applications. High specificity with antigen affinity purification. Provided as liquid form, 1 mg/mL concentration, stored at 4°C or -20°C. For resear...
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 10 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human ADRA1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550123 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gorilla (100%); Monkey, Marmoset (95%); Mouse, Hamster, Elephant (85%) - For IHC(P): Use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis.
Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH).
This receptor also acts as a proto-oncogene when constitutively activated, inducing neoplastic transformation.
It is expressed in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen.
ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-32660_alpha-1b_Adrenergic_Receptor_P35368-1_Rabbit.svg)
(이미지: PA5-32660_alpha-1b_Adrenergic_Receptor_P35368-1_Rabbit_PDP.jpeg)
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