Thermo Fisher Scientific KSV Cyclin D Monoclonal Antibody (94B)
Cyclin D 단백질을 검출하기 위한 Rat 모노클론 항체입니다. Western blot, ICC/IF, IP 등 다양한 어세이에 적용 가능합니다. 단백질 A로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 보관을 권장합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific KSV Cyclin D Monoclonal Antibody (94B)
Applications
- Western Blot (WB): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rat / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 94B |
| Immunogen | Recombinant fusion protein produced from a clone from KSV |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1957438 |
Product Specific Information
MA1-91431 detects D type cyclin from virus samples.
Target Information
This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with Cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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