Thermo Fisher Scientific Cdc6 Monoclonal Antibody (6-36)
Cdc6 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. Western Blot과 Immunoprecipitation에 최적화되어 있으며, DNA 복제 개시 조절 연구에 유용. 1 mg/mL 액상 형태로 제공되며 4°C 또는 -20°C에서 보관.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5 µg/mL |
| Immunoprecipitation (IP) | 1 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6-36 |
| Immunogen | Recombinant human Cdc6 protein and fusing the splenocytes with NS1/Ag4-1 mouse myeloma cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2078532 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in the cell nucleus during cell cycle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during the cell cycle is regulated through its phosphorylation by Cdks. Transcription of this protein is regulated in response to mitogenic signals through transcriptional control mechanisms involving E2F proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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