Thermo Fisher Scientific Fc Receptor Binding Inhibitor Polyclonal Antibody, Functional Grade, eBioscience
상품 옵션 정보 | |||||||||
---|---|---|---|---|---|---|---|---|---|
카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
16-9161-38 | - | Thermo Fisher Scientific 16-9161-38 Fc Receptor Binding Inhibitor Polyclonal Antibody, Functional Grade, eBioscience 5 mg pk | 재고문의 | pk | 4,660,000원 | - | 5,126,000원 | ||
16-9161-73 | - | Thermo Fisher Scientific 16-9161-73 Fc Receptor Binding Inhibitor Polyclonal Antibody, Functional Grade, eBioscience 100 tests pk | 재고문의 | pk | 561,000원 | - | 617,100원 | ||
16-9161-025 | - | Thermo Fisher Scientific 16-9161-025 Fc Receptor Binding Inhibitor Polyclonal Antibody, Functional Grade, eBioscience 25 mg pk | 재고문의 | pk | 0원 | - | 0원 | ||
16-9161-050 | - | Thermo Fisher Scientific 16-9161-050 Fc Receptor Binding Inhibitor Polyclonal Antibody, Functional Grade, eBioscience 50 mg pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
20 µL/test
View 9 publications 9 publications
Immunoprecipitation (IP)
-
View 1 publication 1 publication
Functional Assay (Functional)
Assay-Dependent
Control (Ctrl)
Assay-Dependent
Inhibition Assays (IA)
-
View 1 publication 1 publication
Blocking Assay (BLOCK)
-
View 1 publication 1 publication
Product Specifications
Published species
Human
Class
Polyclonal
Type
Antibody
Conjugate
Functional Grade Functional Grade Functional Grade
Form
Liquid
Concentration
20 µL/Test
Storage conditions
4° C
Shipping conditions
Wet ice
RRID
AB_2866336
Product Specific Information
Description: The human FcgammaR-binding inhibitor can be used to inhibit the non-specific Fc-gamma receptor (FcgammaR)-mediated binding of mouse monoclonal antibodies used for flow cytometric analysis of human tissue. Four different classes of Fcgamma receptors have been identified: FcgammaRI (CD64), FcgammaRII (CD32), and FcgammaRIII (CD16), and they are expressed at varying levels in multiple cell lineages including high expression in myeloid, granulocyte and B cells. The biological function of the FcgammaR, including initiation of endocytosis, phagocytosis and antigen presentation, is elicited upon binding of host-immunoglobulin. The extent to which mouse monoclonal antibodies will bind to human FcgammaR varies depending on the isotype of the monoclonal antibody. Furthermore, different monoclonal antibodies of the same isotype will display different binding to human FcgammaRs.
Applications Reported: FG Purified Human Fc Receptor Binding Inhibitor has been reported for use in flow cytometric analysis.
To inhibit the non-specific binding of mouse monoclonal antibodies add the human Fc Receptor Binding Inhibitor to samples and incubate on ice for 20 minutes. Without washing proceed to stain with primary antibody.
Applications Tested: FG Purified Human FcgR-Binding Inhibitor has been pre-titrated and tested by inhibiting binding of fluorochrome-conjugated isotype controls to U937 cells. This can be used at 20 µL per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Storage and handling: Use in a sterile environment.
Filtration: 0.2 µm post-manufacturing filtered.
Purity: Greater than 90%, as determined by SDS-PAGE.
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
Aggregation: Less than 10%, as determined by HPLC.
Target Information
Four different classes of Fcy receptors have been identified: FcyRI (CD64), FcyRII (CD32), and FcyRIII (CD16), and they are expressed at varying levels in multiple cell lineages including high expression in myeloid, granulocyte and B cells. The biological function of the FcyR, including initiation of endocytosis, phagocytosis and antigen presentation, is elicited upon binding of host-immunoglobulin. The extent to which mouse monoclonal antibodies will bind to human FcyR varies depending on the isotype of the monoclonal antibody. Furthermore, different monoclonal antibodies of the same isotype will display different binding to human FcyRs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
배송/결제/교환/반품 안내
배송 정보
기본 배송비 |
| 교환/반품 배송비 |
|
---|---|---|---|
착불 배송비 |
| ||
교환/반품 배송비 |
|
결제 및 환불 안내
결제 방법 |
|
---|---|
취소 |
|
반품 |
|
환급 |
|
교환 및 반품 접수
교환 및 반품 접수 기한 |
|
---|---|
교환 및 반품 접수가 가능한 경우 |
|
교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
교환 절차 |
|
---|---|
반품 절차 |
|