Thermo Fisher Scientific REV1 Monoclonal Antibody (OTI1E12), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The REV1 gene encodes a protein similar to the S. cerevisiae mutagenesis protein Rev1.
Rev1 proteins contain a BRCT domain, essential for protein-protein interactions.
Human Rev1-like protein is suggested to act as a scaffold recruiting DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.
Two alternatively spliced transcript variants encoding different proteins have been identified.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.