Thermo Fisher Scientific WIPI1 Monoclonal Antibody (OTI8F9), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

WIPI1 (WD repeat domain, phosphoinositide interacting-1) is involved in autophagy and may regulate protein trafficking in recycling pathways.
It contains three WD repeats forming a 7-bladed propeller structure with a conserved motif that mediates protein interactions.
WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network.
It is ubiquitously expressed, with highest levels in heart, testis, placenta, pancreas, and skeletal muscle.
Upregulation in various tumors suggests a potential role in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.