Thermo Fisher Scientific PON1 Monoclonal Antibody (OTI2D4), TrueMAB
Thermo Fisher Scientific의 PON1 Monoclonal Antibody (OTI2D4)은 인간 PON1 단백질을 인식하는 Mouse IgG2b 항체로, WB, IHC, ICC, Flow, ELISA에 사용 가능. 고순도 친화 크로마토그래피 정제, 트레할로스 포함 PBS 버퍼에 동결건조 형태로 제공. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D4 |
| Immunogen | Full length human recombinant protein of human PON1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Available Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The paraoxonase (PON) gene family in humans includes three members: PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is primarily synthesized in the liver and secreted into plasma, associated with HDL.
It hydrolyzes active metabolites of organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism may contribute to neurodegeneration and serve as an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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