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Thermo Fisher Scientific BECN1 Monoclonal Antibody (OTI3F3), TrueMAB
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BECN1 단백질을 인식하는 단클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. Human 및 Rat 시료에 반응하며, 동결건조 형태로 제공됩니다. 자가포식 관련 연구에 활용 가능합니다.
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마지막 업데이트 2025. 08. 04. 오후 04:15
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Thermo Fisher Scientific CF502527 BECN1 Monoclonal Antibody (OTI3F3), TrueMAB 100 ug pk판매 단위 pk ·
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784,000원VAT 포함 862,400원
Thermo Fisher Scientific · Thermo Fisher Scientific BECN1 Monoclonal Antibody (OTI3F3), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F3 |
| Immunogen | Full length human recombinant protein of human BECN1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Beclin 1 plays a central role in autophagy as a core subunit of the PI3K complex that mediates phosphatidylinositol 3-phosphate formation.
Different PI3K complex forms are involved in various membrane trafficking pathways:
- PI3KC3-C1: Initiation of autophagosomes
- PI3KC3-C2: Maturation of autophagosomes and endocytosis
Beclin 1 is also implicated in antiviral host defense mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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