Thermo Fisher Scientific GBA3 Monoclonal Antibody (OTI5G5), TrueMAB
Human GBA3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC(P), Flow Cytometry에 적합합니다. 무보존제, 동결건조 형태로 제공되며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–150 and 370–469 of human GBA3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
GBA3 (cytosolic beta-glucosidase, EC 3.2.1.21) is a liver enzyme that hydrolyzes beta-D-glucoside and beta-D-galactoside but not physiologic beta-glycosides, suggesting a role in detoxification of plant glycosides.
It also shows neutral glycosylceramidase activity (EC 3.2.1.62), indicating involvement in a nonlysosomal catabolic pathway of glucosylceramide metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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