Thermo Fisher Scientific RASGRP1 Polyclonal Antibody
Human RASGRP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합하며 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제되어 안정적인 액상 형태로 제공. 연구용으로 Ras 신호전달 및 면역세포 분화 연구에 활용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RASGRP1. Recombinant protein control fragment (Product #RP-106113). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790614 |
Product Specific Information
Immunogen sequence:
RKTAQDTLYV LPSPTSPCPS PVLVRKRAFV KWENKDSLIK SKEELRHLRL PTYQELEQEI NTLKADNDAL KIQLKYAQKK IESLQLEKSN HVLAQMEQGD
Target Information
Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras. Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways. Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses. May also function in differentiation of other cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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