Thermo Fisher Scientific TMC7 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human TMC7 protein. Validated for Western blot and immunohistochemistry. Lyophilized form for flexible storage. Suitable for research use only. Stable with glycerol addition.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:2,000 |
| Immunohistochemistry (IHC) | 1:400–1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TMC7 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10709565 |
Product Specific Information
Glycerol (1:1) may be added for additional stability.
Target Information
TMC7 (Transmembrane channel-like protein 7) is a 723 amino acid protein belonging to the TMC protein family. All TMC genes encode transmembrane proteins with intracellular amino- and carboxy-termini and at least eight membrane-spanning domains. TMC7 is a multi-pass membrane protein that may function as an ion channel or transporter. The gene encoding TMC7 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. Mutations in genes on chromosome 16 are associated with conditions such as giant axonal neuropathy, Rubinstein-Taybi syndrome, and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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