Thermo Fisher Scientific SCAMP2 Polyclonal Antibody
SCAMP2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC(P), ICC/IF에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 40% 글리세롤이 포함되어 안정성이 우수합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCAMP2. Recombinant protein control fragment (Product #RP-91153). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646981 |
Product Specific Information
Immunogen sequence:
DPVDVNPFQD PSVTQLTNAP QGGLAEFNPF SETNAATTVP VTQLPGSSQP AVLQPSVEPT QPTPQAVVSA AQAGLLRQQE ELDRKAAELE RKERELQNTV ANLHV
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs are concentrated in compartments responsible for recycling of cell surface receptors and endocytosis.
In neurons, SCAMPs are associated with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs consist of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs:
- SCAMPs 1–3 contain cytoplasmic N-terminal regions with NPF repeats that interact with EH domain proteins involved in vesicle budding.
- SCAMPs 4 and 5 lack NPF repeats.
- SCAMPs 1–4 are ubiquitously coexpressed, while SCAMP 5 is brain-specific and expressed late in development, coinciding with synapse maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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