Thermo Fisher Scientific ULK3 Recombinant Rabbit Monoclonal Antibody (5Z7Z6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5Z7Z6

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 373-472 of human ULK3 (Q6PHR2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ULK3,uniProtId:Q6PHR2-1,ncbiNodeId:9606,antigenRange:373-472,antigenLength:472,antigenImageFileName:MA5-42879_ULK3_Q6PHR2-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42879_ULK3_Q6PHR2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912020

Product Specific Information

Immunogen sequence: KPRLLAALEV ASAAMAKEEA AGGEQDALDL YQHSLGELLL LLAAEPPGRR RELLHTEVQN LMARAEYLKE QVKMRESRWE ADTLDKEGLS ESVRSSCTLQ

Target Information

ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.