Thermo Fisher Scientific AMPA 4 Polyclonal Antibody
AMPA 4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 비결합형 상태로 동결건조되어 제공됩니다. 신경전달 및 신경가소성 연구용으로 최적화된 항체입니다.
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- OSA00106W-100UL
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 1st extracellular domain of rat Glutamate receptor 4 (AMPA 4) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: AMPA 4.
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA and kainate/AMPA receptors, both containing glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits (GluR-1 to -7). Kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission by glutamate, while NMDA receptors exhibit slower kinetics and higher Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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