Thermo Fisher Scientific Kininogen 1 Polyclonal Antibody
Human Kininogen 1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/40% glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KNG1. Recombinant protein control fragment (Product #RP-100524). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789122 |
Product Specific Information
Immunogen sequence:
LFLTPDCKSL WNGDTGECTD NAYIDIQLRI ASFSQNCDIY PGKDFVQPPT KICVGCPRDI PTNSPELEET LTHTITKLNA ENNATFYFKI DNVKKARVQV VAGKKYFIDF VARETTCSKE SNEELTESCE TK
Target Information
This gene uses alternative splicing to generate two different proteins—high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK).
HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Bradykinin, a peptide causing numerous physiological effects, is released from HMWK.
In contrast, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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