
Thermo Fisher Scientific LARG Polyclonal Antibody
Thermo Fisher Scientific의 LARG Polyclonal Antibody는 인간 단백질 ARHGEF12에 특이적으로 반응하는 rabbit polyclonal 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 항원 친화 정제 방식으로 제조되었습니다. 4°C에서 보관하며 연구용으로 적합합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1350 and 1400 of human leukemia-associated rho guanine nucleotide exchange factor (ARHGEF12, UniProt ID: Q9NZN5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli acting through G protein-coupled receptors.
The encoded protein (ARHGEF12) may form a complex with G proteins and stimulate Rho-dependent signaling pathways.
This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia.
Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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