Thermo Fisher Scientific LARG Polyclonal Antibody
Rabbit polyclonal antibody targeting human leukemia-associated Rho GEF (ARHGEF12). Validated for WB and IP applications. Supplied in liquid form at 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life. For research use only.
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Thermo Fisher Scientific LARG Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1350 and 1400 of human leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12, UniProt ID: Q9NZN5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli acting through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. It has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A301-959A-M_ARHGEF12_Q9NZN5-1_Rabbit.svg, A301-959A-M_ARHGEF12_Q9NZN5-1_Rabbit_PDP.jpeg)
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