Thermo Fisher Scientific CD25 Monoclonal Antibody (P4A10)
개 및 활성화된 T 세포에서 CD25(IL-2Rα)를 인식하는 Mouse IgG1 단클론 항체. Western blot 및 유세포분석에 적합하며, 단백질 A로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | P4A10 |
| Immunogen | Enriched and stimulated Canine T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745297 |
Product Specific Information
Mouse anti-Dog CD25, clone P4A10 recognizes the canine homologue of the human CD25 cell surface antigen, also known as IL-2Rα, a glycoprotein of approximately 55 kDa expressed primarily by activated T lymphocytes (Abrams et al., 2010).
Target Information
CD25 (IL2 receptor alpha chain / IL2RA) is a cytokine receptor involved in the proliferation of T and B lymphocytes. The IL2RA forms part of a heterotrimeric complex with IL2RB and IL2RG, constituting the high-affinity IL2 receptor. Homodimeric IL2RA chains result in low-affinity receptors, while IL2RB homodimers produce medium-affinity receptors. IL2 is primarily produced by mature T cells and functions as a growth, differentiation, and survival factor. It stimulates B cell proliferation, enhances NK cell activity, and regulates immune responses. Mutations in IL2RA are associated with interleukin-2 receptor alpha deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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