Thermo Fisher Scientific SPR Polyclonal Antibody
SPR 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC/IF, IP 등 다양한 응용 가능. Human 및 Mouse 반응성 검증 완료. 1 mg/mL 농도의 액상 시약으로 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Thermo Fisher Scientific SPR Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 65–261 of SPR (Uniprot ID: P35270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153773 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2
- Predicted reactivity: Rabbit (86%), Rhesus Monkey (97%), Bovine (82%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4).
Mutations in this gene result in DOPA-responsive dystonia due to sepiapterin reductase deficiency.
A pseudogene has been identified on chromosome 1.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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