Thermo Fisher Scientific PSMA6 Polyclonal Antibody
PSMA6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. Rat, Human, Mouse에 반응하며 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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- PA522288
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat, Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment containing a sequence corresponding to a region within amino acids 57–246 of Proteasome 20S alpha 6 (PSMA6, UniProt ID: P60900-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11157668 |
Product Specific Information
- Recommended Positive Controls: 293T, A431, H1299, HeLa, mouse liver, rat liver
- Predicted Reactivity:
Mouse (100%), Rat (100%), Xenopus laevis (87%), Pig (98%), Chicken (96%), Sheep (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%) - Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core is composed of four rings of 28 non-identical subunits: two rings of seven alpha subunits and two rings of seven beta subunits. Proteasomes are abundant in eukaryotic cells and function in an ATP/ubiquitin-dependent, non-lysosomal peptide degradation pathway. The immunoproteasome variant plays a key role in processing class I MHC peptides. The PSMA6 gene encodes a 20S core alpha subunit belonging to the peptidase T1A family. A pseudogene is present on the Y chromosome.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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