Thermo Fisher Scientific Human BMI-1 Synthetic Peptide
Human BMI-1 단백질의 중심부 15개 아미노산 서열 기반 합성 펩타이드로, PA5-20223 항체의 블로킹 펩타이드로 사용 가능. PRC1 복합체 연구에 활용되며, 액상 형태로 제공. PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함, -20°C 보관.
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Thermo Fisher Scientific Human BMI-1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human BMI-1.
PEP-0336 can be used as a blocking peptide with polyclonal antibody PA5-20223.
Target Information
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.
PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A (Lys-119), rendering chromatin heritably changed in its expressibility.
In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
주의사항
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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