Thermo Fisher Scientific Human IL-32 Synthetic Peptide
Human IL-32 단백질의 C-말단 15개 아미노산을 기반으로 한 합성 펩타이드. 폴리클로날 항체 PA5-20221과 함께 블로킹 펩타이드로 사용 가능. 인간 IL-32 관련 염증 및 면역 연구에 적합. 연구용으로만 사용.
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Thermo Fisher Scientific Human IL-32 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human IL-32.
PEP-0334 can be used as a blocking peptide with polyclonal antibody PA5-20221.
Target Information
Interleukin-32 (IL-32) was initially identified as a transcript (NK4) selectively expressed in lymphocytes and NK cells, with expression increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and renamed IL-32.
IL-32 is unique in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms.
Treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-α, IL-8, and MIP-2. It is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-γ. Therefore, IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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