Thermo Fisher Scientific COMP Recombinant Rabbit Monoclonal Antibody (2H3R5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2H3R5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human COMP (NP_000086.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COMP,uniProtId:P49747-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:757,antigenImageFileName:MA5-51253_COMP_P49747-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51253_COMP_P49747-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.56 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094301

Product Specific Information

Immunogen sequence: ELLRQQVREI TFLKNTVMEC DACGMQQSVR TGLPSVRPLL HCAPGFCFPG VACIQTESGA RCGPCPAGFT GNGSHCTDVN ECNAHPCFPR VRCINTSPGF R

Target Information

COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.