Thermo Fisher Scientific Talin 1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TLN1. Recombinant protein control fragment (Product #RP-88634). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Talin 1,uniProtId:Q9Y490-1,ncbiNodeId:9606,antigenRange:1775-1879,antigenLength:2541,antigenImageFileName:PA5-82162_Talin_1_Q9Y490-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82162_Talin_1_Q9Y490-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789323

Product Specific Information

Immunogen sequence: LLYTAKEAGG NPKQAAHTQE ALEEAVQMMT EAVEDLTTTL NEAASAAGVV GGMVDSITQA INQLDEGPMG EPEGSFVDYQ TTMVRTAKAI AVTVQEMVTK SNTSP

Target Information

Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.