Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI2C7), TrueMAB
BAG5 단백질을 표적으로 하는 고특이성 단클론 항체로 Western blot에 적합. Human, Mouse, Rat 반응성. Lyophilized 형태로 안정적 보관 가능. 연구용으로 세포사멸 및 hsp70 관련 기작 연구에 활용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C7 |
| Immunogen | Full length human recombinant protein of human BAG5 produced in 293T |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
BAG-5 protein is hypothesized to induce the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function.
It is believed that BAG-5 plays an important role in neuronal death mechanisms and may modulate the hsp70/hsp40 chaperone axis or interact with other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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