Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI2C7), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

BAG-5 protein is hypothesized to induce the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function.
It is believed that BAG-5 plays an important role in neuronal death mechanisms and may modulate the hsp70/hsp40 chaperone axis or interact with other BAG-containing proteins via BAG-BAG heterodimerization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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