Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Recombinant Rabbit Monoclonal Antibody (GH/8215R)
성장호르몬(GH) 표지용 재조합 토끼 단클론 항체로, 인체 시료에 반응합니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, CHO 세포에서 발현된 IgG 카파형 항체입니다. 단백질 A/G 정제, 보존제 없음, -20°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | GH/8215R |
| Immunogen | Recombinant full-length human GH1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17, sharing a high degree of sequence identity.
Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
hGH is produced by somatotroph cells in the pituitary and acts through cytokine receptor subfamily membrane receptors.
Its major role in stimulating body growth involves promoting liver and other tissues to secrete IGF-1, stimulating myoblast differentiation and proliferation, and enhancing amino acid uptake and protein synthesis.
Mutations or deletions in the gene can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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