Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI1B12), TrueMAB
인간 TGIF1 단백질을 표적으로 하는 마우스 단일클론 항체로 Western blot 및 IHC(P) 실험에 적합. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B12 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. It inhibits 9-cis-retinoic acid-dependent RXR alpha transcription activation and acts as a transcriptional co-repressor of SMAD2. TGIF may play a role in nuclear signal transmission during development and adulthood. Mutations are associated with holoprosencephaly type 4, a structural anomaly of the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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