Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI2F5), TrueMAB
TGIF1 단백질을 인식하는 Mouse IgG1 모노클로날 항체로, Western blot에 최적화됨. 인간 TGIF1 재조합 단백질을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F5 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. TGIF1 acts as a transcriptional co-repressor of SMAD2 and may participate in nuclear signal transmission during development and adulthood. Mutations in TGIF1 are associated with holoprosencephaly type 4, a structural brain anomaly.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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