Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI4D10), TrueMAB
인간 TGIF1 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 사용 가능. 비결합형 액상 형태로, PBS/BSA/glycerol 버퍼에 보존. SMAD2 전사 억제 연구 및 발달 관련 신호전달 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D10 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. TGIF functions as a transcriptional co-repressor of SMAD2 and may be involved in nuclear signaling during development and adulthood. Mutations in TGIF1 are associated with holoprosencephaly type 4, a structural anomaly of the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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