Thermo Fisher Scientific APBA2 Polyclonal Antibody
APBA2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. Alzheimer’s disease 관련 연구에 유용. 항원 친화 크로마토그래피로 정제된 고순도 항체.
- 카탈로그번호
- A305220A
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 to 175 of human Amyloid beta A4 precursor protein-binding family A member 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer’s disease.
It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer’s disease patients.
APBA2 is believed to be involved in signal transduction and vesicular trafficking, coupling synaptic vesicle exocytosis to neuronal cell adhesion.
Recent reports suggest that it may also be a candidate gene for autism.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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