Thermo Fisher Scientific HTR2A VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1362)
HTR2A 단백질을 표적으로 하는 알파카 유래 재조합 단일클론 항체입니다. CHO 세포에서 발현되며, 금속 킬레이트 크로마토그래피로 정제되었습니다. 인간 시료에 반응하며 IP 등 연구용으로 적합합니다. 보존제 무첨가, 4°C 또는 -20°C 보관.
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Thermo Fisher Scientific HTR2A VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1362)
Applications
- Immunoprecipitation (IP)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1362 |
| Immunogen | Recombinant Human HTR2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility. It acts through G protein-coupled receptors known as 5-HT (or SR) receptors. The SR-2 receptor family includes SR-2A, SR-2B, and SR-2C, which activate phospholipase C and mobilize intracellular calcium in response to serotonin.
- SR-2A: Involved in tracheal smooth muscle contraction, bronchoconstriction, and aldosterone production; associated with psychiatric disorders such as depression and schizophrenia.
- SR-2B: Expressed in cardiovascular tissues, gut, and brain; plays a role in cardiac pathology.
- SR-2C: Mediates effects of atypical antipsychotic drugs.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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