Thermo Fisher Scientific IgE VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1191)
Recombinant alpaca monoclonal antibody specific for human IgE; suitable for ELISA and SPR assays; produced in CHO cells; purified via metal-chelate chromatography; provided as liquid form at 2 mg/mL concentration for research use only.
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Thermo Fisher Scientific IgE VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1191)
Applications
- ELISA (ELISA): Assay-dependent
- Surface Plasmon Resonance (SPR): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1191 |
| Immunogen | Recombinant Human IgE/IGHE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
Product Specific Information
- Compatible with Direct ELISA
Target Information
IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with four Ig-like constant domains and two light chains.
IgE plays an essential role in type I hypersensitivity reactions (such as hay fever, asthma, hives, and anaphylactic shock) by binding to Fc receptors on basophils and mast cells.
Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils, promoting allergic manifestations.
IgE is also functionally important for immunity against parasites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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