Thermo Fisher Scientific SQSTM1 Recombinant Superclonal Antibody (11HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1–3 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies. Each lot is produced with a known mixture of light and heavy chains, ensuring consistent performance and eliminating variability typical of polyclonal antibody production.

Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

The SQSTM1 gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the NF-κB signaling pathway. It acts as a scaffolding/adaptor protein with TNF receptor-associated factor 6 to mediate NF-κB activation. Mutations in this gene are associated with sporadic and familial Paget disease of bone. Multiple alternatively spliced transcript variants exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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